Augmentation of the contact allergen-mediated sensitization in Mdr1-/-,Mrp1-/-,Mrp5-/-,Itih5-/-and Itih5-/-/Mrp5-/-mouse models as well as in murine and human 3D skin models

项目来源

德(略)基(略)F(略)

项目主持人

J(略) (略)t(略)a(略);

项目受资助机构

U(略)e(略)t(略)k(略)i(略) (略)h(略)

立项年度

2(略)

立项时间

未(略)

项目编号

3(略)2(略)7

项目级别

国(略)

研究期限

未(略) (略)

受资助金额

0(略)欧(略)

学科

D(略)A(略)O(略)

学科代码

未(略)

基金类别

R(略)a(略) (略)n(略)

关键词

未(略)

参与者

H(略) (略)e(略)

参与机构

未(略)

项目标书摘要:In(略),combined(略)ure to co(略)gens and (略)s very co(略) studies (略)dence tha(略) augment (略)ment of a(略)tact derm(略)cially ag(略)sensitizi(略)es.Previo(略)to this p(略)ed an imp(略) of multi(略)ance rela(略)s(MRPs)MD(略) MRP5 as (略) heavy ch(略))in the p(略) of aller(略) dermatit(略)hown that(略)ion as tr(略)of contac(略) and hyal(略)tants can(略)he expres(略) transpor(略)in skin c(略)h the rel(略)okines.In(略)t has bee(略)ted that (略)interacts(略)ronan pla(略)tant role(略) type hyp(略)ty respon(略)skin.Ther(略)nt to stu(略)ct of top(略)ied conta(略)s(eugenol(略)isothiazo(略)out or in(略)n with su(略)at could (略)gmentatio(略)odium lau(略)hyalurona(略)ylhexyl p(略) Mdr1-/-,(略)5-/-,Itih(略)h5-/-/Mrp(略)t mouse m(略)otypic mu(略)n models (略)ased knoc(略)fectants (略)mmunohist(略)microarra(略)From thes(略)e anticip(略) insight (略)lex inter(略)kin irrit(略)ntact all(略)he pathog(略)czematous(略)pe hypers(略)responses(略)an skin a(略)blishment(略)stems to (略)ugmentati(略)

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